Muscle wasting after Grapiprant (Galliprant) in dogs
49 reports to the FDA describe muscle wasting in dogs given Grapiprant. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
49Reports
67%Marked serious
6.1%Recovered
16%Died or euthanised
28 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).
Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.
Questions owners ask
- Can Grapiprant cause muscle wasting in dogs?
- 49 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 28 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Muscle wasting with similar medicines
- Muscle wasting after Carprofen (Rimadyl) 150 reports · 0.3% of its reports
- Muscle wasting after Deracoxib (Deramaxx) 32 reports · 0.3% of its reports
- Muscle wasting after Meloxicam (Metacam) 21 reports · 0.3% of its reports
All reported side effects of Grapiprant in dogs · Medicines most reported with muscle wasting