Eye or vision problems after Grapiprant (Galliprant) in dogs

The FDA has received 49 reports of eye or vision problems in dogs after Grapiprant. That is 0.6% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

49Reports
94%Marked serious
22%Recovered
16%Died or euthanised
27 daysTypical onset
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How soon it started

Same day
3 10%
1–2 days
6 21%
3–7 days
2 6.9%
1–4 weeks
4 14%
Over a month
14 48%

How the animals did

Recovered
7 14%
Recovered with lasting effects
4 8.2%
Still unwell when reported
19 39%
Died
1 2.0%
Euthanised
7 14%
Not known
11 22%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
2
8–11 years
21
12+ years
24

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause eye or vision problems in dogs?
49 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 27 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye or vision problems with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with eye or vision problems