Difficulty to rise after Grapiprant (Galliprant) in dogs

75 reports to the FDA describe difficulty to rise in dogs given Grapiprant. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

75Reports
55%Marked serious
6.7%Recovered
21%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
14 22%
1–2 days
16 25%
3–7 days
4 6.2%
1–4 weeks
8 12%
Over a month
23 35%

How the animals did

Recovered
5 6.7%
Still unwell when reported
40 53%
Died
3 4.0%
Euthanised
13 17%
Not known
14 19%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
0
4–7 years
4
8–11 years
32
12+ years
36

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause difficulty to rise in dogs?
75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Difficulty to rise with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with difficulty to rise