Dehydration after Grapiprant (Galliprant) in dogs

159 reports to the FDA describe dehydration in dogs given Grapiprant. That is 1.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

159Reports
69%Marked serious
18%Recovered
25%Died or euthanised
17 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
18 14%
1–2 days
21 16%
3–7 days
15 11%
1–4 weeks
20 15%
Over a month
57 44%

How the animals did

Recovered
28 18%
Recovered with lasting effects
1 0.6%
Still unwell when reported
62 39%
Died
6 3.8%
Euthanised
33 21%
Not known
29 18%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
7
4–7 years
16
8–11 years
60
12+ years
75

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause dehydration in dogs?
159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 17 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with dehydration