Dehydration after Deracoxib (Deramaxx) in dogs

The FDA has received 533 reports of dehydration in dogs after Deracoxib. That is 4.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

533Reports
30%Marked serious
7.9%Recovered
43%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
8 7.2%
1–2 days
13 12%
3–7 days
30 27%
1–4 weeks
28 25%
Over a month
32 29%

How the animals did

Recovered
40 7.5%
Recovered with lasting effects
2 0.4%
Still unwell when reported
42 7.9%
Died
178 33%
Euthanised
51 9.6%
Not known
220 41%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
79
4–7 years
171
8–11 years
197
12+ years
67

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause dehydration in dogs?
533 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with dehydration