Kidney problems after Deracoxib (Deramaxx) in dogs

The FDA has received 2,212 reports of kidney problems in dogs after Deracoxib. That is 20% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

2,212Reports

19%Marked serious

4.2%Recovered

34%Died or euthanised

10 daysTypical onset

How soon it started

Same day

28 8.6%

1–2 days

35 11%

3–7 days

77 24%

1–4 weeks

65 20%

Over a month

119 37%

How the animals did

Recovered

83 3.8%

Recovered with lasting effects

11 0.5%

Still unwell when reported

188 8.5%

Died

646 29%

Euthanised

106 4.8%

Not known

1,178 53%

Problems reported at the same time

1,079 49%

1,019 46%

827 37%

756 34%

739 33%

567 26%

438 20%

414 19%

Age of the animals

Under 1 year

1–3 years

247

4–7 years

489

8–11 years

779

12+ years

607

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause kidney problems in dogs?: 2,212 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Carprofen (Rimadyl) 5,760 reports · 12% of its reports
Kidney problems after Grapiprant (Galliprant) 842 reports · 9.6% of its reports
Kidney problems after Meloxicam (Metacam) 1,011 reports · 13% of its reports
Kidney problems after Firocoxib (Previcox) 1,407 reports · 18% of its reports

All reported side effects of Deracoxib in dogs · Medicines most reported with kidney problems