Hyperphosphataemia after Deracoxib (Deramaxx) in dogs

The FDA has received 610 reports of hyperphosphataemia in dogs after Deracoxib. That is 5.5% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

610Reports
21%Marked serious
4.3%Recovered
48%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
4 4.0%
1–2 days
13 13%
3–7 days
32 32%
1–4 weeks
17 17%
Over a month
33 33%

How the animals did

Recovered
23 3.8%
Recovered with lasting effects
3 0.5%
Still unwell when reported
44 7.2%
Died
257 42%
Euthanised
38 6.2%
Not known
245 40%

Problems reported at the same time

Age of the animals

Under 1 year
25
1–3 years
78
4–7 years
149
8–11 years
214
12+ years
141

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause hyperphosphataemia in dogs?
610 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with hyperphosphataemia