Lethargy after Deracoxib (Deramaxx) in dogs

The FDA has received 2,435 reports of lethargy in dogs after Deracoxib. That is 22% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

2,435Reports
20%Marked serious
7.2%Recovered
35%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
53 13%
1–2 days
56 13%
3–7 days
90 21%
1–4 weeks
96 23%
Over a month
128 30%

How the animals did

Recovered
164 6.7%
Recovered with lasting effects
11 0.5%
Still unwell when reported
182 7.5%
Died
724 30%
Euthanised
133 5.5%
Not known
1,221 50%

Problems reported at the same time

Age of the animals

Under 1 year
85
1–3 years
302
4–7 years
655
8–11 years
902
12+ years
474

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause lethargy in dogs?
2,435 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with lethargy