Cough after Grapiprant (Galliprant) in dogs

The FDA has received 110 reports of cough in dogs after Grapiprant. That is 1.3% of all reports for this medicine, compared with 0.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

110Reports
54%Marked serious
13%Recovered
18%Died or euthanised
94 daysTypical onset
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How soon it started

Same day
11 13%
1–2 days
9 11%
3–7 days
6 7.1%
1–4 weeks
6 7.1%
Over a month
52 62%

How the animals did

Recovered
14 13%
Still unwell when reported
49 45%
Died
5 4.5%
Euthanised
15 14%
Not known
27 25%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
3
4–7 years
10
8–11 years
33
12+ years
60

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause cough in dogs?
110 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 94 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cough with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with cough