Abnormal posture after Grapiprant (Galliprant) in dogs

The FDA has received 56 reports of abnormal posture in dogs after Grapiprant. That is 0.6% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

56Reports
55%Marked serious
20%Recovered
32%Died or euthanised
19 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
12 24%
1–2 days
2 4.1%
3–7 days
5 10%
1–4 weeks
10 20%
Over a month
20 41%

How the animals did

Recovered
10 18%
Recovered with lasting effects
1 1.8%
Still unwell when reported
15 27%
Died
1 1.8%
Euthanised
17 30%
Not known
12 21%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
7
8–11 years
21
12+ years
26

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause abnormal posture in dogs?
56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal posture with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with abnormal posture