Urinary incontinence after Fluralaner (Bravecto) in dogs

The FDA has received 275 reports of urinary incontinence in dogs after Fluralaner. That is 0.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

275Reports
83%Marked serious
28%Recovered
17%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
44 28%
1–2 days
39 24%
3–7 days
27 17%
1–4 weeks
13 8.1%
Over a month
37 23%

How the animals did

Recovered
59 21%
Recovered with lasting effects
18 6.5%
Still unwell when reported
115 42%
Died
11 4.0%
Euthanised
35 13%
Not known
37 13%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
61
4–7 years
76
8–11 years
56
12+ years
58

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause urinary incontinence in dogs?
275 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with urinary incontinence