Excessive thirst after Fluralaner (Bravecto) in dogs

634 reports to the FDA describe excessive thirst in dogs given Fluralaner. That is 0.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

634Reports

79%Marked serious

25%Recovered

15%Died or euthanised

2 daysTypical onset

How soon it started

Same day

127 28%

1–2 days

142 31%

3–7 days

65 14%

1–4 weeks

43 9.4%

Over a month

82 18%

How the animals did

Recovered

126 20%

Recovered with lasting effects

31 4.9%

Still unwell when reported

285 45%

Died

36 5.7%

Euthanised

59 9.3%

Not known

97 15%

Problems reported at the same time

281 44%

231 36%

201 32%

198 31%

139 22%

111 18%

94 15%

84 13%

Age of the animals

Under 1 year

1–3 years

125

4–7 years

192

8–11 years

180

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause excessive thirst in dogs?: 634 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Afoxolaner (NexGard) 422 reports · 0.7% of its reports
Excessive thirst after Sarolaner (Simparica) 93 reports · 0.6% of its reports
Excessive thirst after Lotilaner (Credelio) 106 reports · 1.1% of its reports
Excessive thirst after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 30 reports · 0.3% of its reports
Excessive thirst after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 22 reports · 0.7% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with excessive thirst