Excessive urination after Fluralaner (Bravecto) in dogs

374 reports to the FDA describe excessive urination in dogs given Fluralaner. That is 0.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

374Reports
85%Marked serious
22%Recovered
16%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
62 23%
1–2 days
80 30%
3–7 days
31 11%
1–4 weeks
32 12%
Over a month
66 24%

How the animals did

Recovered
55 15%
Recovered with lasting effects
28 7.5%
Still unwell when reported
172 46%
Died
26 7.0%
Euthanised
35 9.4%
Not known
58 16%

Problems reported at the same time

Age of the animals

Under 1 year
27
1–3 years
67
4–7 years
113
8–11 years
105
12+ years
56

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause excessive urination in dogs?
374 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with excessive urination