Deafness after Florfenicol + Mometasone + Terbinafine in dogs

225 reports to the FDA describe deafness in dogs given Florfenicol + Mometasone + Terbinafine. That is 6.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

225Reports

96%Marked serious

21%Recovered

2.7%Died or euthanised

1 daysTypical onset

How soon it started

Same day

73 38%

1–2 days

47 25%

3–7 days

26 14%

1–4 weeks

23 12%

Over a month

21 11%

How the animals did

Recovered

36 16%

Recovered with lasting effects

11 4.9%

Still unwell when reported

63 28%

Died

1 0.4%

Euthanised

5 2.2%

Not known

109 48%

Problems reported at the same time

Wobbliness (ataxia)

41 18%

Loss of appetite

39 17%

Lethargy

37 16%

Didn't work as expected

36 16%

Vomiting

30 13%

Behaviour change

29 13%

Head tilt - ear disorder

26 12%

Tympanic rupture

20 8.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause deafness in dogs?: 225 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

Deafness after Cefpodoxime 49 reports · 1.2% of its reports
Deafness after Isoflurane 21 reports · 0.8% of its reports
Deafness after Cephalexin 22 reports · 0.8% of its reports
Deafness after Clotrimazole + Gentamicin + Mometasone 804 reports · 31% of its reports
Deafness after Betamethasone + Florfenicol + Terbinafine 182 reports · 7.4% of its reports
Deafness after Genta Momet Clotrim 1,446 reports · 63% of its reports
Deafness after Ketoconazole 87 reports · 3.9% of its reports
Deafness after Betamethasone + Clotrimazole + Gentamicin 1,165 reports · 59% of its reports
Deafness after Neomycin + Triamcinolone 126 reports · 27% of its reports
Deafness after Genta Betamet Clotrim 245 reports · 57% of its reports

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with deafness