Deafness after Cefpodoxime in dogs

The FDA has received 49 reports of deafness in dogs after Cefpodoxime. That is 1.2% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

49Reports
76%Marked serious
18%Recovered
4.1%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
7 20%
1–2 days
5 14%
3–7 days
2 5.7%
1–4 weeks
11 31%
Over a month
10 29%

How the animals did

Recovered
5 10%
Recovered with lasting effects
4 8.2%
Still unwell when reported
13 27%
Euthanised
2 4.1%
Not known
25 51%

Problems reported at the same time

Tympanic rupture
5 10%
Abnormal menace reflex test
4 8.2%

Age of the animals

Under 1 year
1
1–3 years
2
4–7 years
2
8–11 years
19
12+ years
23

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause deafness in dogs?
49 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with deafness