Deafness after Betamethasone + Florfenicol + Terbinafine in dogs

182 reports to the FDA describe deafness in dogs given Betamethasone + Florfenicol + Terbinafine. That is 7.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

182Reports

96%Marked serious

44%Recovered

1.6%Died or euthanised

7 daysTypical onset

How soon it started

Same day

34 22%

1–2 days

32 20%

3–7 days

28 18%

1–4 weeks

35 22%

Over a month

29 18%

How the animals did

Recovered

61 34%

Recovered with lasting effects

19 10%

Still unwell when reported

38 21%

Euthanised

3 1.6%

Not known

61 34%

Problems reported at the same time

Ear discharge

13 7.1%

Hearing decreased

12 6.6%

Didn't work as expected

9 4.9%

Behaviour change

8 4.4%

Lethargy

7 3.8%

Partial deafness

7 3.8%

Application site reaction

7 3.8%

Head tilt - ear disorder

6 3.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Florfenicol + Terbinafine cause deafness in dogs?: 182 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

Deafness after Cefpodoxime 49 reports · 1.2% of its reports
Deafness after Florfenicol + Mometasone + Terbinafine 225 reports · 6.4% of its reports
Deafness after Isoflurane 21 reports · 0.8% of its reports
Deafness after Cephalexin 22 reports · 0.8% of its reports
Deafness after Clotrimazole + Gentamicin + Mometasone 804 reports · 31% of its reports
Deafness after Genta Momet Clotrim 1,446 reports · 63% of its reports
Deafness after Ketoconazole 87 reports · 3.9% of its reports
Deafness after Betamethasone + Clotrimazole + Gentamicin 1,165 reports · 59% of its reports
Deafness after Neomycin + Triamcinolone 126 reports · 27% of its reports
Deafness after Genta Betamet Clotrim 245 reports · 57% of its reports

All reported side effects of Betamethasone + Florfenicol + Terbinafine in dogs · Medicines most reported with deafness