Deafness after Ketoconazole in dogs

The FDA has received 87 reports of deafness in dogs after Ketoconazole. That is 3.9% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

87Reports
92%Marked serious
31%Recovered
1.1%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
10 14%
1–2 days
15 21%
3–7 days
23 32%
1–4 weeks
13 18%
Over a month
10 14%

How the animals did

Recovered
14 16%
Recovered with lasting effects
13 15%
Still unwell when reported
23 26%
Euthanised
1 1.1%
Not known
36 41%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
1
4–7 years
13
8–11 years
39
12+ years
32

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause deafness in dogs?
87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

All reported side effects of Ketoconazole in dogs · Medicines most reported with deafness