Didn't work as expected after Ketoconazole in dogs

485 reports to the FDA describe didn't work as expected in dogs given Ketoconazole. That is 21% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported unusually often with this medicine.

485Reports

42%Marked serious

7.0%Recovered

2.7%Died or euthanised

21 daysTypical onset

How soon it started

Same day

32 9.7%

1–2 days

24 7.3%

3–7 days

30 9.1%

1–4 weeks

116 35%

Over a month

127 39%

How the animals did

Recovered

33 6.8%

Recovered with lasting effects

1 0.2%

Still unwell when reported

202 42%

Died

3 0.6%

Euthanised

10 2.1%

Not known

236 49%

Problems reported at the same time

39 8.0%

35 7.2%

34 7.0%

33 6.8%

30 6.2%

30 6.2%

Skin rash or irritation

27 5.6%

Underdose

24 4.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

157

8–11 years

159

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause didn't work as expected in dogs?: 485 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Melarsomine (Immiticide) 646 reports · 2.8% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 698 reports · 13% of its reports
Didn't work as expected after Diphenhydramine 585 reports · 12% of its reports
Didn't work as expected after Butorphanol 1,022 reports · 23% of its reports
Didn't work as expected after Cefpodoxime 671 reports · 17% of its reports
Didn't work as expected after Tramadol 475 reports · 13% of its reports
Didn't work as expected after Florfenicol + Mometasone + Terbinafine 969 reports · 27% of its reports
Didn't work as expected after Desoxycorticosterone Pivalate 355 reports · 11% of its reports
Didn't work as expected after Propofol 600 reports · 20% of its reports
Didn't work as expected after Dirlotapide 712 reports · 25% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with didn't work as expected