Deafness after Betamethasone + Clotrimazole + Gentamicin in dogs

1,165 reports to the FDA describe deafness in dogs given Betamethasone + Clotrimazole + Gentamicin. That is 59% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,165Reports

16%Marked serious

3.6%Recovered

1.5%Died or euthanised

3 daysTypical onset

How soon it started

Same day

41 15%

1–2 days

63 24%

3–7 days

98 37%

1–4 weeks

51 19%

Over a month

12 4.5%

How the animals did

Recovered

28 2.4%

Recovered with lasting effects

14 1.2%

Still unwell when reported

204 18%

Died

16 1.4%

Euthanised

1 0.1%

Not known

902 77%

Problems reported at the same time

Pr-ear(s), lesion(s)

41 3.5%

Partial deafness

20 1.7%

Death

16 1.4%

External ear disorder

10 0.9%

Lethargy

8 0.7%

Didn't work as expected

6 0.5%

Wobbliness (ataxia)

5 0.4%

Vestibular disorder

5 0.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

134

8–11 years

452

12+ years

438

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Clotrimazole + Gentamicin cause deafness in dogs?: 1,165 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

Deafness after Cefpodoxime 49 reports · 1.2% of its reports
Deafness after Florfenicol + Mometasone + Terbinafine 225 reports · 6.4% of its reports
Deafness after Isoflurane 21 reports · 0.8% of its reports
Deafness after Cephalexin 22 reports · 0.8% of its reports
Deafness after Clotrimazole + Gentamicin + Mometasone 804 reports · 31% of its reports
Deafness after Betamethasone + Florfenicol + Terbinafine 182 reports · 7.4% of its reports
Deafness after Genta Momet Clotrim 1,446 reports · 63% of its reports
Deafness after Ketoconazole 87 reports · 3.9% of its reports
Deafness after Neomycin + Triamcinolone 126 reports · 27% of its reports
Deafness after Genta Betamet Clotrim 245 reports · 57% of its reports

All reported side effects of Betamethasone + Clotrimazole + Gentamicin in dogs · Medicines most reported with deafness