Vomiting after Fipronil + Pyriproxyfen + S-methoprene in dogs

89 reports to the FDA describe vomiting in dogs given Fipronil + Pyriproxyfen + S-methoprene. That is 21% of all reports for this medicine, compared with 28% across reports for all dog medicines.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Fipronil kills fleas and ticks (spot-on).

Questions owners ask

Can Fipronil + Pyriproxyfen + S-methoprene cause vomiting in dogs?

89 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 12 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

• Vomiting after Spinosad (Comfortis) 30,909 reports · 54% of its reports
• Vomiting after Lufenuron + Milbemycin Oxime (Sentinel) 4,725 reports · 18% of its reports
• Vomiting after Imidacloprid + Moxidectin (Advantage Multi) 1,904 reports · 15% of its reports
• Vomiting after Nitenpyram (Capstar) 1,204 reports · 11% of its reports
• Vomiting after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 1,925 reports · 19% of its reports
• Vomiting after Fipronil + S-methoprene (Frontline Plus) 627 reports · 21% of its reports
• Vomiting after Flumethrin + Imidacloprid (Seresto) 295 reports · 13% of its reports
• Vomiting after Imidacloprid 251 reports · 13% of its reports
• Vomiting after Fipronil 417 reports · 30% of its reports
• Vomiting after Lufenuron 325 reports · 32% of its reports

All reported side effects of Fipronil + Pyriproxyfen + S-methoprene in dogs · Medicines most reported with vomiting