Walking difficulty after Diphenhydramine in dogs

The FDA has received 51 reports of walking difficulty in dogs after Diphenhydramine. That is 1.1% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can Diphenhydramine cause walking difficulty in dogs?

51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 1 day of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Walking difficulty with similar medicines

• Walking difficulty after Melarsomine (Immiticide) 72 reports · 0.3% of its reports
• Walking difficulty after Polysulfated Glycosaminoglycan 71 reports · 1.3% of its reports
• Walking difficulty after Butorphanol 42 reports · 0.9% of its reports
• Walking difficulty after Cefpodoxime 40 reports · 1.0% of its reports
• Walking difficulty after Tramadol 88 reports · 2.3% of its reports
• Walking difficulty after Florfenicol + Mometasone + Terbinafine 62 reports · 1.8% of its reports
• Walking difficulty after Isoflurane 28 reports · 1.0% of its reports
• Walking difficulty after Cephalexin 45 reports · 1.7% of its reports
• Walking difficulty after Famotidine 52 reports · 2.0% of its reports
• Walking difficulty after Chondroitin + Glucosamine 53 reports · 2.0% of its reports

All reported side effects of Diphenhydramine in dogs · Medicines most reported with walking difficulty