Cough after Diphenhydramine in dogs

104 reports to the FDA describe cough in dogs given Diphenhydramine. That is 2.2% of all reports for this medicine, compared with 0.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

104Reports
65%Marked serious
18%Recovered
14%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
35 40%
1–2 days
10 11%
3–7 days
5 5.7%
1–4 weeks
12 14%
Over a month
25 29%

How the animals did

Recovered
17 16%
Recovered with lasting effects
2 1.9%
Still unwell when reported
50 48%
Died
6 5.8%
Euthanised
9 8.7%
Not known
20 19%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
28
4–7 years
24
8–11 years
32
12+ years
10

About this medicine

Type: medicine.

Questions owners ask

Can Diphenhydramine cause cough in dogs?
104 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cough with similar medicines

All reported side effects of Diphenhydramine in dogs · Medicines most reported with cough