Pacing after Cyphenothrin + Fipronil + S-methoprene in dogs
The FDA has received 20 reports of pacing in dogs after Cyphenothrin + Fipronil + S-methoprene. That is 3.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.
20Reports
90%Marked serious
55%Recovered
0.0%Died or euthanised
3 daysTypical onset
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Fipronil kills fleas and ticks (spot-on).
Questions owners ask
- Can Cyphenothrin + Fipronil + S-methoprene cause pacing in dogs?
- 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 3 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Pacing with similar medicines
- Pacing after Spinosad (Comfortis) 67 reports · 0.1% of its reports
- Pacing after Lufenuron + Milbemycin Oxime (Sentinel) 45 reports · 0.2% of its reports
- Pacing after Imidacloprid + Moxidectin (Advantage Multi) 77 reports · 0.6% of its reports
- Pacing after Nitenpyram (Capstar) 33 reports · 0.3% of its reports
- Pacing after Fipronil + S-methoprene (Frontline Plus) 24 reports · 0.8% of its reports
All reported side effects of Cyphenothrin + Fipronil + S-methoprene in dogs · Medicines most reported with pacing
