Anxiety after Cyphenothrin + Fipronil + S-methoprene in dogs
39 reports to the FDA describe anxiety in dogs given Cyphenothrin + Fipronil + S-methoprene. That is 6.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.
39Reports
87%Marked serious
62%Recovered
0.0%Died or euthanised
30 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Fipronil kills fleas and ticks (spot-on).
Questions owners ask
- Can Cyphenothrin + Fipronil + S-methoprene cause anxiety in dogs?
- 39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 30 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Anxiety with similar medicines
- Anxiety after Spinosad (Comfortis) 141 reports · 0.2% of its reports
- Anxiety after Lufenuron + Milbemycin Oxime (Sentinel) 113 reports · 0.4% of its reports
- Anxiety after Imidacloprid + Moxidectin (Advantage Multi) 103 reports · 0.8% of its reports
- Anxiety after Nitenpyram (Capstar) 63 reports · 0.6% of its reports
- Anxiety after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 36 reports · 0.4% of its reports
- Anxiety after Fipronil + S-methoprene (Frontline Plus) 36 reports · 1.2% of its reports
- Anxiety after Flumethrin + Imidacloprid (Seresto) 23 reports · 1.0% of its reports
- Anxiety after Fipronil 23 reports · 1.6% of its reports
All reported side effects of Cyphenothrin + Fipronil + S-methoprene in dogs · Medicines most reported with anxiety