Nausea after Cyclosporine (Atopica) in dogs

The FDA has received 149 reports of nausea in dogs after Cyclosporine. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

149Reports

34%Marked serious

32%Recovered

6.0%Died or euthanised

1 daysTypical onset

How soon it started

Same day

30 48%

1–2 days

7 11%

3–7 days

5 7.9%

1–4 weeks

7 11%

Over a month

14 22%

How the animals did

Recovered

46 31%

Recovered with lasting effects

2 1.3%

Still unwell when reported

23 15%

Died

4 2.7%

Euthanised

5 3.4%

Not known

69 46%

Problems reported at the same time

71 48%

43 29%

35 23%

33 22%

16 11%

16 11%

Restlessness or agitation

15 10%

Liver problems

12 8.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause nausea in dogs?: 149 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Nausea with similar medicines

Nausea after Oclacitinib (Apoquel) 130 reports · 0.4% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with nausea