Drooling after Cyclosporine (Atopica) in dogs

150 reports to the FDA describe drooling in dogs given Cyclosporine. That is 1.0% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

150Reports

43%Marked serious

25%Recovered

11%Died or euthanised

5 daysTypical onset

How soon it started

Same day

17 29%

1–2 days

9 15%

3–7 days

8 14%

1–4 weeks

6 10%

Over a month

19 32%

How the animals did

Recovered

35 23%

Recovered with lasting effects

2 1.3%

Still unwell when reported

18 12%

Died

9 6.0%

Euthanised

8 5.3%

Not known

78 52%

Problems reported at the same time

49 33%

43 29%

37 25%

37 25%

26 17%

18 12%

Restlessness or agitation

17 11%

Death

17 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause drooling in dogs?: 150 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drooling with similar medicines

Drooling after Oclacitinib (Apoquel) 266 reports · 0.9% of its reports
Drooling after Ilunocitinib (Zenrelia) 32 reports · 1.5% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with drooling