Drooling after Oclacitinib (Apoquel) in dogs

266 reports to the FDA describe drooling in dogs given Oclacitinib. That is 0.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

266Reports

48%Marked serious

19%Recovered

13%Died or euthanised

7 daysTypical onset

How soon it started

Same day

49 24%

1–2 days

29 14%

3–7 days

32 16%

1–4 weeks

37 18%

Over a month

54 27%

How the animals did

Recovered

50 19%

Still unwell when reported

137 52%

Died

5 1.9%

Euthanised

30 11%

Not known

44 17%

Problems reported at the same time

82 31%

78 29%

77 29%

43 16%

40 15%

38 14%

35 13%

35 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause drooling in dogs?: 266 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drooling with similar medicines

Drooling after Cyclosporine (Atopica) 150 reports · 1.0% of its reports
Drooling after Ilunocitinib (Zenrelia) 32 reports · 1.5% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with drooling