Loose stool after Cyclosporine (Atopica) in dogs

The FDA has received 341 reports of loose stool in dogs after Cyclosporine. That is 2.2% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

341Reports

23%Marked serious

11%Recovered

6.7%Died or euthanised

6 daysTypical onset

How soon it started

Same day

24 28%

1–2 days

12 14%

3–7 days

8 9.4%

1–4 weeks

15 18%

Over a month

26 31%

How the animals did

Recovered

37 11%

Recovered with lasting effects

1 0.3%

Still unwell when reported

51 15%

Died

18 5.3%

Euthanised

5 1.5%

Not known

229 67%

Problems reported at the same time

138 40%

70 21%

68 20%

60 18%

30 8.8%

27 7.9%

Restlessness or agitation

24 7.0%

Itching

24 7.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

139

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause loose stool in dogs?: 341 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loose stool with similar medicines

Loose stool after Oclacitinib (Apoquel) 284 reports · 1.0% of its reports
Loose stool after Ilunocitinib (Zenrelia) 25 reports · 1.1% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with loose stool