Blood in stool after Cyclosporine (Atopica) in dogs

The FDA has received 98 reports of blood in stool in dogs after Cyclosporine. That is 0.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

98Reports

28%Marked serious

6.1%Recovered

24%Died or euthanised

17 daysTypical onset

How soon it started

Same day

1 4.5%

1–2 days

3 14%

3–7 days

2 9.1%

1–4 weeks

11 50%

Over a month

5 23%

How the animals did

Recovered

6 6.1%

Still unwell when reported

8 8.2%

Died

13 13%

Euthanised

11 11%

Not known

60 61%

Problems reported at the same time

49 50%

37 38%

33 34%

30 31%

26 27%

24 24%

20 20%

14 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause blood in stool in dogs?: 98 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in stool with similar medicines

Blood in stool after Oclacitinib (Apoquel) 61 reports · 0.2% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with blood in stool