Underdose after Clomipramine (Clomicalm) in dogs

27 reports to the FDA describe underdose in dogs given Clomipramine. That is 1.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
19%Marked serious
26%Recovered
0.0%Died or euthanised
124 daysTypical onset
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How soon it started

Same day
3 20%
1–2 days
0 0.0%
3–7 days
0 0.0%
1–4 weeks
1 6.7%
Over a month
11 73%

How the animals did

Recovered
7 26%
Still unwell when reported
10 37%
Not known
10 37%

Problems reported at the same time

Drug administration error
4 15%
Hyperkalaemia
2 7.4%
Unpalatable
2 7.4%
2 7.4%

Age of the animals

Under 1 year
1
1–3 years
8
4–7 years
9
8–11 years
3
12+ years
5

About this medicine

Clomipramine treats separation anxiety.

Products with this ingredient include Clomicalm. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Clomipramine cause underdose in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 124 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

All reported side effects of Clomipramine in dogs · Medicines most reported with underdose