Swelling after Amoxicillin in dogs

76 reports to the FDA describe swelling in dogs given Amoxicillin. That is 5.6% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

76Reports

57%Marked serious

6.6%Recovered

28%Died or euthanised

7 daysTypical onset

How soon it started

Same day

11 20%

1–2 days

9 17%

3–7 days

9 17%

1–4 weeks

17 31%

Over a month

8 15%

How the animals did

Recovered

5 6.6%

Still unwell when reported

23 30%

Died

8 11%

Euthanised

13 17%

Not known

27 36%

Problems reported at the same time

26 34%

23 30%

20 26%

19 25%

19 25%

13 17%

13 17%

11 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause swelling in dogs?: 76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Amoxicillin + Clavulanate (Clavamox) 454 reports · 8.4% of its reports
Swelling after Doxycycline 288 reports · 7.2% of its reports
Swelling after Cefovecin (Convenia) 362 reports · 9.6% of its reports
Swelling after Enrofloxacin (Baytril) 323 reports · 8.6% of its reports
Swelling after Metronidazole 238 reports · 7.7% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with swelling