Swelling after Metronidazole in dogs

238 reports to the FDA describe swelling in dogs given Metronidazole. That is 7.7% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

238Reports

64%Marked serious

23%Recovered

19%Died or euthanised

2 daysTypical onset

How soon it started

Same day

75 35%

1–2 days

40 19%

3–7 days

33 15%

1–4 weeks

35 16%

Over a month

31 14%

How the animals did

Recovered

53 22%

Recovered with lasting effects

1 0.4%

Still unwell when reported

108 45%

Died

14 5.9%

Euthanised

32 13%

Not known

30 13%

Problems reported at the same time

96 40%

95 40%

90 38%

68 29%

59 25%

47 20%

45 19%

42 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause swelling in dogs?: 238 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Amoxicillin + Clavulanate (Clavamox) 454 reports · 8.4% of its reports
Swelling after Doxycycline 288 reports · 7.2% of its reports
Swelling after Cefovecin (Convenia) 362 reports · 9.6% of its reports
Swelling after Enrofloxacin (Baytril) 323 reports · 8.6% of its reports
Swelling after Amoxicillin 76 reports · 5.6% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with swelling