Elevated cholesterol (total) after Amoxicillin in dogs

24 reports to the FDA describe elevated cholesterol (total) in dogs given Amoxicillin. That is 1.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

63%Marked serious

0.0%Recovered

25%Died or euthanised

26 daysTypical onset

How soon it started

Same day

2 13%

1–2 days

1 6.3%

3–7 days

2 13%

1–4 weeks

4 25%

Over a month

7 44%

How the animals did

Still unwell when reported

10 42%

Died

1 4.2%

Euthanised

5 21%

Not known

8 33%

Problems reported at the same time

21 88%

11 46%

10 42%

9 38%

9 38%

9 38%

Elevated lipase

9 38%

Excessive thirst

7 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause elevated cholesterol (total) in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 26 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

Elevated cholesterol (total) after Amoxicillin + Clavulanate (Clavamox) 68 reports · 1.3% of its reports
Elevated cholesterol (total) after Doxycycline 35 reports · 0.9% of its reports
Elevated cholesterol (total) after Enrofloxacin (Baytril) 38 reports · 1.0% of its reports
Elevated cholesterol (total) after Metronidazole 38 reports · 1.2% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with elevated cholesterol (total)