Excessive thirst after Amoxicillin in dogs

The FDA has received 67 reports of excessive thirst in dogs after Amoxicillin. That is 5.0% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

67Reports
73%Marked serious
6.0%Recovered
19%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
6 14%
1–2 days
2 4.5%
3–7 days
6 14%
1–4 weeks
12 27%
Over a month
18 41%

How the animals did

Recovered
4 6.0%
Still unwell when reported
36 54%
Died
8 12%
Euthanised
5 7.5%
Not known
14 21%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
6
4–7 years
18
8–11 years
21
12+ years
21

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause excessive thirst in dogs?
67 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

All reported side effects of Amoxicillin in dogs · Medicines most reported with excessive thirst