Urinary incontinence after Amoxicillin + Clavulanate (Clavamox) in dogs

117 reports to the FDA describe urinary incontinence in dogs given Amoxicillin + Clavulanate. That is 2.2% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

117Reports
53%Marked serious
6.8%Recovered
21%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
13 18%
1–2 days
9 12%
3–7 days
7 9.5%
1–4 weeks
25 34%
Over a month
20 27%

How the animals did

Recovered
6 5.1%
Recovered with lasting effects
2 1.7%
Still unwell when reported
52 44%
Died
10 8.5%
Euthanised
14 12%
Not known
33 28%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
8
4–7 years
22
8–11 years
44
12+ years
34

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause urinary incontinence in dogs?
117 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with urinary incontinence