Urinary incontinence after Amoxicillin in dogs

The FDA has received 40 reports of urinary incontinence in dogs after Amoxicillin. That is 3.0% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
73%Marked serious
2.5%Recovered
33%Died or euthanised
23 daysTypical onset
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How soon it started

Same day
3 11%
1–2 days
2 7.4%
3–7 days
4 15%
1–4 weeks
7 26%
Over a month
11 41%

How the animals did

Recovered
1 2.5%
Still unwell when reported
22 55%
Died
6 15%
Euthanised
7 18%
Not known
4 10%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
3
4–7 years
8
8–11 years
10
12+ years
18

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause urinary incontinence in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 23 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Amoxicillin in dogs · Medicines most reported with urinary incontinence