Splenomegaly after Amoxicillin + Clavulanate (Clavamox) in dogs
The FDA has received 32 reports of splenomegaly in dogs after Amoxicillin + Clavulanate. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
32Reports
63%Marked serious
0.0%Recovered
53%Died or euthanised
17 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Amoxicillin treats bacterial infections.
Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Amoxicillin + Clavulanate cause splenomegaly in dogs?
- 32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 17 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Splenomegaly with similar medicines
- Splenomegaly after Doxycycline 33 reports · 0.8% of its reports
- Splenomegaly after Enrofloxacin (Baytril) 30 reports · 0.8% of its reports
- Splenomegaly after Metronidazole 29 reports · 0.9% of its reports
All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with splenomegaly