Abnormal ultrasound finding after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 192 reports of abnormal ultrasound finding in dogs after Amoxicillin + Clavulanate. That is 3.6% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

192Reports
67%Marked serious
6.8%Recovered
30%Died or euthanised
22 daysTypical onset
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How soon it started

Same day
13 9.7%
1–2 days
13 9.7%
3–7 days
17 13%
1–4 weeks
32 24%
Over a month
59 44%

How the animals did

Recovered
12 6.3%
Recovered with lasting effects
1 0.5%
Still unwell when reported
78 41%
Died
23 12%
Euthanised
34 18%
Not known
44 23%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
25
4–7 years
50
8–11 years
66
12+ years
43

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause abnormal ultrasound finding in dogs?
192 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 22 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with abnormal ultrasound finding