Abnormal ultrasound finding after Doxycycline in dogs

The FDA has received 104 reports of abnormal ultrasound finding in dogs after Doxycycline. That is 2.6% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

104Reports

82%Marked serious

5.8%Recovered

44%Died or euthanised

22 daysTypical onset

How soon it started

Same day

7 8.8%

1–2 days

9 11%

3–7 days

10 13%

1–4 weeks

20 25%

Over a month

34 43%

How the animals did

Recovered

5 4.8%

Recovered with lasting effects

1 1.0%

Still unwell when reported

43 41%

Died

9 8.7%

Euthanised

37 36%

Not known

9 8.7%

Problems reported at the same time

68 65%

63 61%

60 58%

56 54%

46 44%

43 41%

39 38%

33 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause abnormal ultrasound finding in dogs?: 104 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

Abnormal ultrasound finding after Amoxicillin + Clavulanate (Clavamox) 192 reports · 3.6% of its reports
Abnormal ultrasound finding after Cefovecin (Convenia) 76 reports · 2.0% of its reports
Abnormal ultrasound finding after Enrofloxacin (Baytril) 141 reports · 3.7% of its reports
Abnormal ultrasound finding after Metronidazole 182 reports · 5.9% of its reports
Abnormal ultrasound finding after Amoxicillin 85 reports · 6.3% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with abnormal ultrasound finding