Febrile after Amoxicillin + Clavulanate (Clavamox) in dogs

40 reports to the FDA describe febrile in dogs given Amoxicillin + Clavulanate. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
65%Marked serious
10%Recovered
33%Died or euthanised
17 daysTypical onset
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How soon it started

Same day
4 12%
1–2 days
3 8.8%
3–7 days
6 18%
1–4 weeks
10 29%
Over a month
11 32%

How the animals did

Recovered
4 10%
Still unwell when reported
20 50%
Died
4 10%
Euthanised
9 23%
Not known
3 7.5%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
6
4–7 years
10
8–11 years
14
12+ years
3

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause febrile in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 17 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Febrile with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with febrile