Collapse after Amoxicillin + Clavulanate (Clavamox) in dogs

104 reports to the FDA describe collapse in dogs given Amoxicillin + Clavulanate. That is 1.9% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

104Reports
73%Marked serious
7.7%Recovered
54%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
13 18%
1–2 days
13 18%
3–7 days
12 16%
1–4 weeks
19 26%
Over a month
16 22%

How the animals did

Recovered
8 7.7%
Still unwell when reported
23 22%
Died
31 30%
Euthanised
25 24%
Not known
17 16%

Problems reported at the same time

Age of the animals

Under 1 year
12
1–3 years
13
4–7 years
13
8–11 years
32
12+ years
34

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause collapse in dogs?
104 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with collapse