Collapse after Amoxicillin in dogs

The FDA has received 35 reports of collapse in dogs after Amoxicillin. That is 2.6% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

35Reports

74%Marked serious

14%Recovered

49%Died or euthanised

10 daysTypical onset

How soon it started

Same day

4 18%

1–2 days

3 14%

3–7 days

4 18%

1–4 weeks

8 36%

Over a month

3 14%

How the animals did

Recovered

5 14%

Still unwell when reported

7 20%

Died

11 31%

Euthanised

6 17%

Not known

6 17%

Problems reported at the same time

17 49%

14 40%

14 40%

13 37%

12 34%

11 31%

10 29%

8 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause collapse in dogs?: 35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

Collapse after Amoxicillin + Clavulanate (Clavamox) 104 reports · 1.9% of its reports
Collapse after Doxycycline 89 reports · 2.2% of its reports
Collapse after Cefovecin (Convenia) 102 reports · 2.7% of its reports
Collapse after Enrofloxacin (Baytril) 77 reports · 2.0% of its reports
Collapse after Metronidazole 83 reports · 2.7% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with collapse