Imidacloprid + Pyriproxyfen side effects in cats

655 reports sent to the FDA between 2011 and 2026 involve Imidacloprid + Pyriproxyfen in cats. The most reported problems were itching, hair loss, behaviour change. 37% were marked serious.

655Reports
37%Marked serious
0.0%Only medicine involved
20%Recovered
4.4%Died or euthanised
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About this medicine

Imidacloprid kills fleas (spot-on or collar).

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't stop mites
2 0.3%

How soon problems started

Same day
60 14%
1–2 days
53 12%
3–7 days
48 11%
1–4 weeks
157 37%
Over a month
111 26%

Time from the first dose to the first sign, where both dates were reported (429 reports).

How the animals did

Recovered
132 20%
Still unwell when reported
75 11%
Died
17 2.6%
Euthanised
12 1.8%
Not known
419 64%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other flea and tick treatments for cats