Imidacloprid + Moxidectin (Advantage Multi) side effects in cats
8,157 reports sent to the FDA between 2006 and 2026 involve Imidacloprid + Moxidectin in cats. The most reported problems were itching, drooling, hair loss. 52% were marked serious, and where it was recorded, signs eased after stopping the medicine in 94% of cases.
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (5,455 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Domestic Shorthair 3,956 reports
- Domestic 1,250 reports
- Domestic Longhair 615 reports
- Domestic Mediumhair 390 reports
- Siamese 165 reports
- Maine Coon 131 reports
- Persian 71 reports
- Ragdoll 57 reports
- Himalayan 56 reports
- Bengal 39 reports