Fipronil side effects in cats
503 reports sent to the FDA between 2011 and 2026 involve Fipronil in cats. The most reported problems were vomiting, itching, lethargy. 21% were marked serious.
503Reports
21%Marked serious
0.0%Only medicine involved
33%Recovered
4.8%Died or euthanised
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About this medicine
Fipronil kills fleas and ticks (spot-on).
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (371 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Domestic Shorthair 270 reports
- Domestic Longhair 74 reports
- Domestic Mediumhair 29 reports
- Maine Coon 12 reports
- Siamese 9 reports
- Persian 7 reports
- Domestic 7 reports
- Himalayan 6 reports
- American Shorthair 4 reports
- Cat (other) 3 reports
Other flea and tick treatments for cats
Spinosad (Comfortis)11,584 reports · 6.7% seriousNitenpyram (Capstar)8,744 reports · 11% seriousImidacloprid + Moxidectin (Advantage Multi)8,157 reports · 52% seriousLufenuron1,108 reports · 8.8% seriousFlumethrin + Imidacloprid (Seresto)674 reports · 40% seriousImidacloprid + Pyriproxyfen655 reports · 37% seriousFipronil + S-methoprene (Frontline Plus)367 reports · 22% seriousImidacloprid252 reports · 20% serious