Hiding after Imidacloprid + Moxidectin (Advantage Multi) in cats

307 reports to the FDA describe hiding in cats given Imidacloprid + Moxidectin. That is 3.8% of all reports for this medicine, compared with 2.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

307Reports
48%Marked serious
45%Recovered
5.5%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
131 64%
1–2 days
30 15%
3–7 days
12 5.9%
1–4 weeks
16 7.8%
Over a month
16 7.8%

How the animals did

Recovered
137 45%
Still unwell when reported
16 5.2%
Died
10 3.3%
Euthanised
7 2.3%
Not known
137 45%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
95
4–7 years
84
8–11 years
53
12+ years
28

About this medicine

Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).

Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Imidacloprid + Moxidectin cause hiding in cats?
307 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hiding with similar medicines

All reported side effects of Imidacloprid + Moxidectin in cats · Medicines most reported with hiding