Accidental exposure after Imidacloprid + Moxidectin (Advantage Multi) in cats

The FDA has received 269 reports of accidental exposure in cats after Imidacloprid + Moxidectin. That is 3.3% of all reports for this medicine, compared with 2.6% across reports for all cat medicines.

269Reports
50%Marked serious
37%Recovered
1.9%Died or euthanised
Same dayTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
109 73%
1–2 days
31 21%
3–7 days
2 1.3%
1–4 weeks
3 2.0%
Over a month
5 3.3%

How the animals did

Recovered
99 37%
Still unwell when reported
12 4.5%
Died
5 1.9%
Not known
153 57%

Problems reported at the same time

Age of the animals

Under 1 year
63
1–3 years
96
4–7 years
45
8–11 years
34
12+ years
15

About this medicine

Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).

Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Imidacloprid + Moxidectin cause accidental exposure in cats?
269 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Accidental exposure with similar medicines

All reported side effects of Imidacloprid + Moxidectin in cats · Medicines most reported with accidental exposure