Vomiting after Imidacloprid + Pyriproxyfen in cats

68 reports to the FDA describe vomiting in cats given Imidacloprid + Pyriproxyfen. That is 10% of all reports for this medicine, compared with 18% across reports for all cat medicines, so it is reported less often than average with this medicine.

68Reports
59%Marked serious
40%Recovered
5.9%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
7 16%
1–2 days
1 2.3%
3–7 days
7 16%
1–4 weeks
19 43%
Over a month
10 23%

How the animals did

Recovered
27 40%
Still unwell when reported
4 5.9%
Died
3 4.4%
Euthanised
1 1.5%
Not known
33 49%

Problems reported at the same time

14 21%
12 18%
12 18%
Dehydration
10 15%

Age of the animals

Under 1 year
15
1–3 years
17
4–7 years
12
8–11 years
11
12+ years
8

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Questions owners ask

Can Imidacloprid + Pyriproxyfen cause vomiting in cats?
68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Imidacloprid + Pyriproxyfen in cats · Medicines most reported with vomiting