Fluralaner + Moxidectin (Bravecto Plus) side effects in cats
3,239 reports sent to the FDA between 2019 and 2026 involve Fluralaner + Moxidectin in cats. The most reported problems were hair loss, application site reaction, itching. 39% were marked serious, and where it was recorded, signs eased after stopping the medicine in 50% of cases.
About this medicine
Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Bravecto Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (2,139 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Domestic Shorthair 2,089 reports
- Domestic Longhair 274 reports
- Domestic Mediumhair 223 reports
- Maine Coon 56 reports
- Siamese 47 reports
- Cat (other) 23 reports
- American Shorthair 23 reports
- Persian 22 reports
- Ragdoll 21 reports
- Bengal 19 reports