Hiding after Fluralaner + Moxidectin (Bravecto Plus) in cats

The FDA has received 114 reports of hiding in cats after Fluralaner + Moxidectin. That is 3.5% of all reports for this medicine, compared with 2.4% across reports for all cat medicines.

114Reports
49%Marked serious
31%Recovered
4.4%Died or euthanised
Same dayTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
58 64%
1–2 days
21 23%
3–7 days
4 4.4%
1–4 weeks
1 1.1%
Over a month
6 6.7%

How the animals did

Recovered
34 30%
Recovered with lasting effects
1 0.9%
Still unwell when reported
67 59%
Died
2 1.8%
Euthanised
3 2.6%
Not known
7 6.1%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
34
4–7 years
33
8–11 years
19
12+ years
13

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).

Products with this combination include Bravecto Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner + Moxidectin cause hiding in cats?
114 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hiding with similar medicines

All reported side effects of Fluralaner + Moxidectin in cats · Medicines most reported with hiding